Search on: PROPROTEIN CONVERTASE 1 
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Descriptor English:   Proprotein Convertase 1 
Descriptor Spanish:   Proproteína Convertasa 1 
Descriptor Portuguese:   Pró-Proteína Convertase 1 
Synonyms English:   Convertase 1, Proprotein
Convertase PC1, Neuroendocrine
Convertase SPC3, Proprotein
Convertase, PC1 Prohormone
Convertase, PC3 Prohormone
Endoprotease, PC1
Endoprotease, PC3
Neuroendocrine Convertase PC1
PC1 Endoprotease
PC1 Prohormone Convertase
PC3 Endoprotease
PC3 Prohormone Convertase
Prohormone Convertase 1
Prohormone Convertase 3
Prohormone Convertase, PC1
Prohormone Convertase, PC3
Proinsulin Convertase 1
Proprotein Convertase SPC3  
Tree Number:   D08.811.277.656.300.760.640
D08.811.277.656.837.500
D08.811.277.656.959.350.640
Definition English:   A CALCIUM-dependent endopeptidase that has specificity for cleavage at ARGININE that is near paired basic residues. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN; PRORENIN; proenkephalins; prodynorphin; prosomatostatin; and PROINSULIN. 
History Note English:   2004; for PC1 PROHORMONE CONVERTASE, NEUROENDOCRINE CONVERTASE PC1, PC3 ENDOPROTEASE, PROHORMONE CONVERTASE 1 use PROPROTEIN CONVERTASE (NM) 1991-2003; for PC1 ENDOPROTEASE & PC3 PROHORMONE CONVERTASE use PROPROTEIN CONVERTASE (NM) 1993-2003; for PROPROTEIN CONVERTASE SPC3 use PROPROTEIN CONVERTASE (NM) 2001-2003; for PROINSULIN CONVERTASE 1 use PROPROTEIN CONVERTASE (NM) 2002-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   38169 
Unique Identifier:   D045664 

Occurrence in VHL:
 

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